Bioactivity | [Des-Tyr1]-gamma-Endorphin is a neuropeptide, which can be found in human cerebrospinal fluid. [Des-Tyr1]-gamma-Endorphin exhibits antidepressant efficacy, facilitates the extinction of active avoidance and attenuates the passive avoidance behavior in rats[1]. |
CAS | 67810-56-4 |
Sequence | Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu |
Shortening | GGFMTSEKSQTPLVTL |
Formula | C74H122N18O25S |
Molar Mass | 1695.93 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Manchanda R, et al., (Des‐tyr1)‐gamma‐endorphin (DTγE) in the treatment of depression: Double‐blind placebo‐controlled trial[J]. Human Psychopharmacology: Clinical and Experimental, 1986, 1(2): 99-102. |